Association of PM2.5 chemical components with metabolome and peak expiratory flow in patients with stable COPD: a panel study.
OBJECTIVE The component‑specific toxicity of fine particulate matter (PM2.5) and the underlying metabolic pathways driving airflow impairment in chronic obstructive pulmonary disease (COPD) remain unclear. We evaluated how specific PM2.5 constituents alter circulating metabolites and mediate short‑term changes in peak...