Author

Yong Luo

2 papers indexed here

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Review Open access Sep 2026

TREM2-directed therapy in Alzheimer’s disease: from therapeutic window to clinical translation

It is proposed that the therapeutic value of TREM2 is best understood through the concept of therapeutic window, and soluble TREM2 (sTREM2) should be interpreted cautiously, as it may reflect receptor shedding, target engagement, microglial state, disease stage, or a combination of these processes rather than serving a...

Qi-Xia Kuang, Shu-Jun Li, Wen-Di Huang et al. · Frontiers in Aging Neuroscie... · 0 citations

Review Sep 2026

From Homing to Repair: Synergistic Mechanisms of Peripherally Administered Mesenchymal Stem Cells for Central Nervous System Diseases.

Three synergistic mechanisms by which peripherally administered MSCs may influence CNS disease outcomes are summarized, including homing, paracrine signaling, and immunomodulation.

Fang Chen, Ying Ge, Li Zhang et al. · Ageing Research Reviews · 0 citations