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Yongqing Li

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Open access Aug 2026

Loss of wbp11 causes multi-system developmental defects: a zebrafish model of VACTERL association

Introduction VACTERL association is a congenital disorder characterized by the non-random co-occurrence of vertebral, anal, cardiac, tracheo-esophageal, renal, and limb anomalies. WBP11 has been identified as a candidate causative gene; however, existing heterozygous Wbp11 knockout mice recapitulate only a subset of th...

Yu Chen, Shiqi You, Ying-Shuo Zhang et al. · 0 citations
Aug 2026

Loss of bves leads to cardiac contractile dysfunction and myocardial mitochondrial damage in zebrafish.

The Popeye domain-containing protein 1 (Popdc1, also known as Bves) is a transmembrane protein whose dysfunction is closely associated with various diseases. Clinical studies have identified that mutations in the bves gene predispose individuals to limb-girdle muscular dystrophy. However, a marked reduction in Bves pro...

Wanwan Cai, Wan-Bang Zhou, Jun-Rong Lei et al. · 0 citations

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