Plant-derived natural products have emerged as important sources of anticancer agents because of their diverse chemical structures and broad biological activities. However, their clinical application is often limited by poor aqueous solubility, low membrane permeability, insufficient tumor selectivity, and systemic tox...
Chang-Qi Shi, Lu-Lu Zhang, Lan Yan et al.· Phytotherapy Research· 0 citations
Highlights What are the main findings? RA-associated gut dysbiosis is characterized by stage-dependent functional ecological remodeling rather than taxonomic shifts alone. Microbiota-derived metabolites connect gut dysbiosis with epithelial barrier dysfunction, innate/adaptive immune imbalance, and joint inflammation....
Xin-Qian Rong, Xiao-Meng Zhang, Yong Tan et al.· Cells· 1 citation
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