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Review Open access Sep 2026

Association Between Rest-Activity Rhythm and Cardiovascular Disease, Cardiovascular Mortality, and All-Cause Mortality: A Systematic Review and Meta-Analysis.

BACKGROUND Disruption in rest-activity rhythm (RAR) is an emerging risk factor for cardiovascular disease (CVD) and mortality, but the strength of evidence is unclear. Therefore, we conducted a systematic review and meta-analysis to assess associations between RAR characteristics and cardiovascular disease incidence or...

Feng-Shuo Chang, Jin-Hao Xu, M. Guo et al. · 0 citations
Open access Jul 2026

Target-centered network pharmacology and molecular docking reveal potential mechanisms and bioactive compounds of Zhigancao Decoction in insomnia–Arrhythmia comorbidity

This study aimed to investigate the potential mechanisms of Zhigancao Decoction (ZGCT) in insomnia–arrhythmia comorbidity using a target-centered network pharmacology and molecular docking approach. In addition, a refined candidate bioactive compound library was constructed. Active components of ZGCT were retrieved fro...

Bolun Xue, Linghui Lu, Yong Wang et al. · 0 citations

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