Author

Yong Yin

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Open access Sep 2026

GWAS-by-Subtraction Resolves Coronary Artery Disease-Related and Model-Defined Residual Genetic Components of Ischaemic Stroke

Background/Objectives: Genetic overlap between any ischaemic stroke (AIS) and coronary artery disease (CAD) can obscure associations less closely tied to coronary risk. We aimed to separate coronary-shared from residual AIS genetic effects. Methods: We applied GWAS-by-subtraction to GIGASTROKE AIS and UK Biobank/CARDIo...

Bin-Yang Wang, Yu-Xue Wang, Yong Yin · Genes · 0 citations

Aug 2026

Multi-omics integration identifies VIM and LGALS3 as apoptosis-associated genes in astrocytes after traumatic brain injury.

In astrocytes after TBI, VIM and LGALS3 modulate migration and apoptotic signaling, representing candidate molecular markers and potential therapeutic targets for secondary brain injury that warrant further validation.

Bin-Yang Wang, Yu-Xue Wang, Wen Cao et al. · Neuroscience · 0 citations