Author

Yong-Zhen Liu

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Review Open access Oct 2026

Marek’s disease virus: mechanistic insights into host immune responses and multilayered immune evasion strategies

ABSTRACT Marek’s disease virus (MDV) is a highly contagious, oncogenic alphaherpesvirus that induces profound immunosuppression and T-cell lymphomas in poultry, serving as a prominent paradigm for investigating virus-induced tumorigenesis and pathogen evolution under vaccine-driven selection pressure. Despite half a ce...

Ke-Xin Gao, Qing-Qing Yu, R. Guo et al. · Journal of Virology · 0 citations

Aug 2026

Recombinant Marek's disease virus expressing the VP2 gene provides effective protection against novel variant infectious bursal disease virus.

It is demonstrated that rMDV-varVP2 provides effective protection against nVarIBDV challenge and represents a promising MDV1-vectored vaccine strategy for controlling nVarIBDV in poultry.

Zibo Zhang, Yun-Tong Chen, W. Fan et al. · Vaccine · 0 citations

Open access Jul 2026

A new recombinant avian metapneumovirus vaccine candidate provides complete protection against the novel variant infectious bursal disease virus in chickens

The findings suggest that rLN16A-nVarVP2 represents a promising live attenuated bivalent vaccine candidate for preventing infections caused by nVarIBDV and aMPV/B.

Ling Meng, Yun-Tong Chen, Meng-Meng Yu et al. · Veterinary Research · 0 citations