Aug 2026
Development of Oncolytic Virus-Proteolysis-Targeting Chimera Conjugates for Tumor Immunotherapy.
In BPAD, the potent and highly selective infection of OVs to tumor cells enhances both cellular uptake and tumor-selective delivery of PROTACs, resulting in a 640-fold increase in the protein degradation efficiency.
Zhixiong Gao, Hanwei Huang, Ying Zhi et al.
· ACS Nano · 0 citations