The abundance of casually captured monocular videos and images on social media provides a valuable source for immersive content creation, where generating novel views from such sparse observations can greatly enhance user experiences. However, producing photorealistic and geometrically consistent views with precise camera control remains challenging when input coverage is extremely limited. Reconstruction-based approaches such as NeRF and 3D Gaussian Splatting (3DGS) deteriorate severely under sparse inputs and fail to explicitly handle occlusions. Generative methods ease data requirements but still struggle with large-baseline view synthesis due to inaccurate or implicit geometric guidance. To overcome these limitations, we introduce UniWorld-View, a unified framework for controllable large-baseline novel view synthesis from monocular inputs. UniWorld-View integrates explicit 3D guidance with generative diffusion modeling to enable precise camera control and geometrically consistent view generation. The geometric guidance is obtained through an occlusion-aware point cloud rendering strategy that resolves visibility ambiguities and provides accurate priors for diffusion-based synthesis. By coupling this rendering strategy with powerful video diffusion backbones, UniWorld-View achieves high-fidelity novel view generation even under extreme camera motions and wide-baseline changes, and can further provide multi-view videos for downstream dynamic 3DGS reconstruction. Experiments on the WorldScore benchmark and zero-shot NVS benchmarks demonstrate the effectiveness of UniWorld-View in controllability, geometric consistency, and visual fidelity.
Haiyang Zhou, Wangbo Yu, Chaoran Feng et al.· 0 citations
Determining molecular structures from spectroscopic data remains fundamentally challenging because the inverse problem is intrinsically underdetermined: individual spectra are sparse, low-dimensional, and encode only partial structural evidence relative to the vast space of possible molecules. We address this challenge by formulating automated structure elucidation as a scalable hypothesis-refinement paradigm that tightly integrates spectral evidence with large-scale molecular priors. To supply structure-resolving NMR signals for multimodal learning, we construct \textbf{QM9SPIN}, a DFT-derived dataset comprising diverse 1D and 2D spectra, including J-coupling, DEPT experiments, and explicit spin--spin interactions. On this foundation, we introduce \textbf{SpectroMol}, a spectrum-to-structure model that proposes chemically valid molecular hypotheses conditioned on multimodal spectral inputs. Complementarily, we develop \textbf{MS-Mol2Mol}, a high-resolution mass-constrained molecular generator that integrates molecular formula, exact mass, and degree of unsaturation within a conditional generative prior trained on 400 million molecules, ensuring global compositional consistency and chemically realistic refinement. The integrated system achieves 93.8\% top-1 accuracy on the simulated benchmark, adapts effectively from simulated to experimental spectra with limited experimental fine-tuning, and further improves experimental predictions through mass-guided refinement, establishing a scalable route toward automated, data-driven organic structure elucidation.
Chengchun Liu, Zhiyuan Yan, Li Yuan et al.· 0 citations
By combining protein language model embeddings with topology-adaptive geometric reasoning, DiConSite offers a reusable framework for residue-level protein interaction analysis and achieves consistently strong and often best-performing results, while improving robustness to structural uncertainty and cross-modal variation.
Shou-Zhi Chen, Zhenchao Tang, Linlin You et al.· IEEE Transactions on Pattern...· 1 citation
HME is presented, a framework that combines multiple views of molecules to improve molecular understanding and design and enables bidirectional navigation of the chemical-linguistic space, achieving consistent improvements across molecular comprehension and design tasks over strong baselines.
Liuzhenghao Lv, Hao Li, Yu Wang et al.· Nature Communications· 0 citations