Gut microbial dysbiosis drives obesity-related metabolic disorders. This study investigated whether arbutin, a phenolic glycoside, alleviates obesity via gut microbiota modulation. In obese mice, arbutin reduced body weight, improved glucose and lipid profiles, suppressed adipogenic and inflammatory gene expression, an...
Cun-Hua Zhao, Jia-Jia Li, Li-Tuo Li et al.· Journal of Agricultural and...· 0 citations
This review systematically delineates the core molecular machinery of ferroptosis, including the system Xc−-glutathione-GPX4 axis, dysregulated iron metabolism, and lipid peroxidation, together with key regulatory networks involving p53, Nrf2, and AMPK.
K. Ren, Yijia An, Kaili Zhou et al.· Journal of Orthopaedic Trans...· 0 citations
Adipose deposition is genetically regulated and acts as a core determinant of meat quality in livestock. Therefore, exploring the gene regulatory mechanisms underlying adipose deposition is essential to advance the research on adipose tissue development and molecular breeding in livestock. To clarify the molecular basi...
Xue-Feng Wei, Xi Shan, Li-Ze Yang et al.· Animal Genetics· 0 citations
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