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Author

Yongzhi Cui

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Sep 2026

Multimodal Repair of Osteoporotic Fractures With an Exosome‐ECM Integrated Hydrogel

Osteoporotic fractures pose a significant clinical challenge in aging societies due to the limited efficacy and high re‐fracture risk associated with conventional treatments. To address this, we developed EXOs@ECM‐SCS, a multifunctional bioactive hydrogel that encapsulates exosomes derived from induced pluripotent stem...

Ziheng Wei, Fen Tang, Wen-Da Xu et al. · 0 citations
Jul 2026

Dual-regulation of mitophagy and cytosolic mtDNA-induced inflammation for the treatment of inflammatory bone loss.

It is demonstrated that combining mitophagy activation with STING inhibition via engineered exosomes offers a promising therapeutic strategy for inflammatory osteoporosis by addressing both mitochondrial dysfunction and chronic inflammation.

Kaiwen Zheng, Benchi Che, Yongzhi Cui et al. · 0 citations

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