Yoo Jin Kim

Differential effects of ginsenosides on Ca2+ regulation in rotenone-treated neuronal and microglial cells

Parkinson’s disease is one of the most common neurodegenerative disorders, and the pesticide rotenone is widely used to model Parkinson’s disease in experimental studies. Rotenone-induced mitochondrial dysfunction is associated with oxidative stress and intracellular Ca2+ ([Ca2+]ᵢ) dysregulation in neuronal systems. L-...