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Author

Yoojin Seo

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Open access Aug 2026

Colon-targeted oral delivery of melatonin for regulating macrophage activity and intestinal barrier in ulcerative colitis

Background Despite its promising therapeutic potential, inefficient site-specific targeting and complex fabrication processes hinder the clinical translation of oral melatonin therapy for ulcerative colitis (UC). Herein, we present Melatonin-Eudragit-Thioketal polymer-based Assembly (META), a dual pH/ROS-responsive ora...

Nhu-Nam Nguyen, Yoojin Seo, T. Nguyen et al. · 0 citations
Open access Aug 2026

Optimization of a Canine Colon Organoid Platform for Modeling Intestinal Injury and Mesenchymal Stem Cell-Mediated Regeneration.

Canine chronic enteropathy (CE) is characterized by persistent mucosal inflammation and impaired barrier function. Despite its high clinical prevalence, research has been hindered by a lack of host-specific intestinal models. Here, we present an optimized canine-derived colon organoid (cCO) culture platform designed fo...

Hee-Jeong Park, Hyeon Seo Lee, Yun-Ji Lee et al. · 0 citations

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