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Yoona Noh

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Open access Sep 2026

eNAMPT-IFITM3 axis links neuroinflammation to γ-secretase activation

Summary Amyloid-β (Aβ) accumulation and neuroinflammation are central features of Alzheimer’s disease (AD), yet the molecular link connecting inflammatory signaling to γ-secretase activation remains poorly understood. Here, using a cell-based gain-of-function screen with a cDNA library, we identify nicotinamide phospho...

J. Hyun, Sun-Min Jung, Yoona Noh et al. · 0 citations

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