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Author

Yoshiaki Tanaka

2 papers indexed here

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Open access Sep 2026

ESRRB: from embryonic development to cancer

ESRRB is an essential orphan nuclear receptor in embryonic development and in the maintenance of pluripotency. It can contribute to the self-renewal capacity of embryonic stem cells by regulating gene networks involved in cell fate decisions, influenced by core transcription factors such as NANOG, SOX2 and OCT4. Mech...

Emma Rocaboy, Shiva Ghadiri, Yoshiaki Tanaka · 0 citations
Open access Sep 2026

Elucidating the role of DEAF1 in neurodevelopment and shared molecular pathways in high-risk autism genes using cortical organoids

Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and intellectual disability (ID), are genetically heterogeneous. DEAF1 has emerged as a key NDD risk gene, with pathogenic variants linked to DEAF1-associated neurodevelopmental disorder (DAND), but its role in human neurodevelopment remains...

Jonghun Kim, Museog Choe, W. Yang et al. · 0 citations

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