Yoshihito Hashino

Turning a Natural Biopolymer-Binding Protein into a Plastic Surface-Recognizing Protein

Direct evolution is used to alter the substrate specificity of the archaeal chitin-binding protein PfChBD2 toward plastics, demonstrating CBMs as evolutionarily adaptable scaffolds capable of recognizing synthetic polymers and highlighting the potential of engineered CBM-based probes for microplastic detection, polymer...