Multi-organ biochemical perturbations induced by chronic benzo[b]fluoranthene exposure involve oxidative stress and inflammatory response in Balb/c mice.
BACKGROUND Benzo[b]fluoranthene (BbF) is a bioaccumulative high-molecular-weight polycyclic aromatic hydrocarbon (PAH) with documented multi-organ toxicity, yet the systemic effects of chronic oral exposure remain poorly characterized. This study tested the hypothesis that prolonged BbF exposure induces dose-dependent...