Author

You-Qing Shen

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Open access Sep 2026

Cholesterol-Modulated, pH Charge-Reversible Rhodamine-Cored Dendrimers for Transcytosis-Mediated Deep Tumor Delivery

Deep and uniform drug penetration into solid tumors remains a critical challenge in nanomedicine, as conventional nanocarriers relying on the enhanced permeability and retention (EPR) effect are largely confined to perivascular regions. While cellular transcytosis offers a promising active transport route to overcome...

Zi-Hao Ye, Zhe-Hao Wang, Yu-Ji Sun et al. · Polymer Science & Techno... · 0 citations

Open access Aug 2026

Blood-brain barrier-penetrant nanotherapy inhibits haem oxygenase-1-mediated ferroptosis for post-resuscitation neuroprotection

Zwitterionic poly (tertiary amine oxide)-based micelles that cross the BBB via transcytosis and deliver artesunate to suppress haem oxygenase-1-driven ferroptosis, restore iron homeostasis and provide neuroprotection after resuscitation are reported.

Mao Zhang, Wen-Bin Zhang, Qiu-Yu Wei et al. · Nature Communications · 0 citations