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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Youhua Liu

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3 papers indexed here

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Open access Oct 2026

Targeting a Novel AREG + Dendritic Cell Alleviates Renal Fibrosis Induced by Ischemia–Reperfusion Injury

ABSTRACT Renal ischemia–reperfusion injury (RIRI) is a major cause of acute tubular damage and a key driver of maladaptive repair and fibrosis. However, the cellular initiators that connect early immune activation to tubular epithelial–mesenchymal transition (EMT) during RIRI remain poorly defined. Here, we established...

Xin Luo, Long-Bin Xiong, Zhao-Hui Zhou et al. · 0 citations
Open access Aug 2026

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

ABSTRACT Acute kidney injury (AKI) is a clinical syndrome associated with severe morbidity and high mortality, for which there are no currently effective therapies. Aging, a state associated with Klotho protein decline, is an independent risk factor for AKI development and progression. Here, we report that Klotho‐deriv...

Xiaoyao Zhang, Shih-Hua Lin, Tianyu Wu et al. · 0 citations
Open access Aug 2026

Integrated single-cell and spatial transcriptomic analyses identify a unique subset of pro-fibrotic macrophage in kidney fibrosis.

INTRODUCTION Acute kidney injury (AKI) is a severe clinical syndrome associated with high morbidity and mortality, and it possesses high risk of progression to chronic kidney disease (CKD). Renal infiltration of inflammatory cells, particularly macrophages, plays a key role in driving the progression from AKI to CKD....

Liuyan Xiao, Yinyi Long, Xue Hong et al. · 0 citations

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