Ultrasound-enhanced exosome secretion and antibody-free SERS profiling for Alzheimer’s disease via iPSC-derived cortical organoids
Exosomes offer a promising vehicle for noninvasive diagnosis of neurodegenerative diseases by carrying multiple biomarkers across the blood-brain barrier. However, traditional exosome analysis often misses subtle genotype-specific variations because of weak signals from a few exosomes, reliance on markers, and limited...