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Author

Yu-Bao Wang

2 papers indexed here

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Sep 2026

Targeting the Snail1-ATGL-Ferroptosis-EMT Axis via AKT-GSK3β Signaling: Low-Dose Colchicine Attenuates Idiopathic Pulmonary Fibrosis.

BACKGROUND The mechanisms underlying colchicine's (COL's) anti-fibrotic effects in idiopathic pulmonary fibrosis (IPF) remain unclear. Ferroptosis-associated redox imbalance and epithelial-mesenchymal transition (EMT) are well-recognized central drivers of IPF progression, yet the upstream regulatory mechanisms linking...

Lei-Lei Shi, Si-Yu Zhan, Xing-Kai Wang et al. · 0 citations
Sep 2026

Unanticipated global emergence and evolution of Pneumocystis jirovecii mutations and resistance driven by a human-targeted drug.

Nearly all known cases of antimicrobial resistance have been linked to agents that directly target microbes. This paradigm overlooks other drivers of microbial evolution and resistance. Here, we report compelling evidence of resistance-associated mutations in Pneumocystis jirovecii, a high-priority fungal pathogen desi...

Liang Ma, Ming Hao, Wei-Zhong Chang et al. · 0 citations

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