Yu-Bing Fu

Microbiota-derived self-adjuvanting exopolysaccharide-based codelivery system for potent cancer immunotherapy

Cancer vaccines hold great promise by eliciting antigen-specific T cell responses against tumors; however, their efficacy remains limited by poor coordination between antigen delivery and innate immune activation. Here, microbiota-derived metabolites (exopolysaccharides, EPSs) are presented as a self-adjuvanting codeli...