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Open access Sep 2026

Diquat exposure disrupts ferroportin-dependent iron homeostasis and drives ferroptosis-associated white matter injury.

Diquat (DQ) is one of the most widely used bipyridyl herbicides and has been identified as a potential neurotoxin; however, its primary central nervous system (CNS) targets and the underlying mechanisms remain unclear. In cases of acute human DQ poisoning, subcortical white matter lesions have been reported to emerge a...

Peng-Yu Bai, Xue-Shan Cao, Song-Han Wang et al. · 0 citations
Review Open access Aug 2026

An exploratory hypoxia signature comprising four genes shows limited external prognostic transferability in esophageal squamous cell carcinoma

The four-gene signature developed showed moderate short-term discrimination in the derivation cohort but weak long-term performance, selection instability, and limited cross-cohort reproducibility, and should be regarded as a hypothesis-generating research signature rather than a platform-independent or clinically depl...

Yu-Bo Liu, Surina Wu, Gang Wu · 0 citations

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