Author

Yu-bo Zhang

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Open access Aug 2026

SESN1 is a negative regulator of MAVS and dynamically expressed during RNA viral infection.

RNA viruses, major pathogens of humans and animals, are responsible for numerous inflammatory diseases. Commonly, mild RNA virus infection fails to trigger inflammatory diseases due to host immune homeostasis. However, severe RNA virus infection destroys immune homeostasis and causes hyperinflammation. The detail mecha...

Qiang-Hui Liu, Peiran Chen, Chun-Yan He et al. · Proceedings of the National... · 0 citations

Review Jul 2026

Targeted protein degradation: bridging chemical biology and clinical translation.

An overview of the developmental trajectory of the TPD field is provided and how diverse modalities can be leveraged to address intracellular, membrane-associated, and extracellular protein targets are discussed.

Yu-bo Zhang, Junwei Fu, Yue Liu et al. · Acta Pharmacologica Sinica · 0 citations