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Yu-Chen Lei

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Sep 2026

Shenghui Decoction Improves Sleep-Deprivation-Induced Cognitive Impairment in Mice by Modulating Neuroinflammation, NRG1/ErbB4 Signaling, and Purine Metabolism.

ETHNOPHARMACOLOGICAL RELEVANCE Shenghui Decoction (SHD) is a traditional Chinese medicine formula first documented by Chen Shiduo in Bian Zheng Lu during the Qing dynasty. It has traditionally been used for disorders related to forgetfulness, insomnia, and mental disturbance. Cognitive impairment induced by sleep depri...

Yu-Chen Lei, Jia-Wei Tan, Mei-Ya Zhang et al. · 0 citations
Open access Sep 2026

Abnormal coordination of executive control network and default mode network in cognitive impairment after deep nuclei intracerebral hemorrhage

Modulating FC between these hub brain regions (R-DLPFC and PCC) may provide new therapeutic strategies for cognitive recovery after DNICH and abnormal coordination of intra-network and inter-network FC of ECN and DMN may represent a shared neural mechanism of cognitive impairment after DNICH.

Xi-Wen Fan, Yu-Chen Lei, Yong-Bing Deng et al. · 0 citations

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