Author

Yu-Fan Wu

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Sep 2026

α7 Nicotinic Acetylcholine Receptor Activation Promotes Anxiety- and Depressive-Like Behaviors Associated With CREB/CRH Signaling in the Hypothalamic Paraventricular Nucleus.

It is found that pharmacological activation of α7 nAChR with PNU282987 induced anxiety- and depressive-like behaviors under control conditions and further exacerbated behavioral abnormalities following chronic restraint stress (CRS), without significantly affecting locomotor activity.

Can-Mao Wang, Rong-Tian Li, Yu-Fan Wu et al. · Neuropharmacology · 0 citations

Open access Jul 2026

Imaging-mediated genetic effects link brain microstructure, metabolic profiles, and regional transcription to glioma susceptibility

Robust multi-layered evidence is provided for the causal roles of white matter microstructural abnormalities, metabolic dysregulation, and regional gene expression in glioma development and indicates that significant regional genes are heavily involved in DNA metabolism and cell cycle pathways.

Yufan Wu, Xuezhen Wang, Xinkai Wang et al. · Frontiers in Immunology · 0 citations