Conventional periodontitis treatments are constrained by challenges such as antibiotic resistance and inadequate tissue regeneration. Herein, we rationally engineer a robust Fe/Mn bimetallic nanozyme (Fe/Mn-Bzyme) derived from a zeolitic imidazolate framework-8 precursor, featuring atomically asymmetric Fe-Mn dual-atom...
Qi-Tao Yu, Yue Zhan, Qiuyue Liu et al.· Acta Biomaterialia· 0 citations
While current dural repair patches achieve mechanical sealing to prevent cerebrospinal fluid leakage, they fail to address the critical pathological cascades of traumatic brain injury, including structural disruption of meningeal lymphatic vessels and dysregulation of neuroimmune responses. Here, we break this therapeu...
Periodontitis is a chronic inflammatory oral disease featured with continuous alveolar bone resorption, where a ccumulated reactive oxygen species (ROS) aggravate tissue damage and local inflammation. Ceria nanoparticles (CNPs) act as promising redox nanozymes with excellent ROS-scavenging and anti-inflammatory capacit...