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Yu-Feng Zhou

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Review Open access Sep 2026

“Gut-Joint Axis” Perspective on Immunometabolic Crosstalk in Osteoarthritis: A Narrative Review of Mechanistic Insights and Targeted Strategies

Abstract Osteoarthritis (OA) is a heterogeneous whole-joint disease in which local mechanical injury interacts with systemic metabolic dysfunction and chronic low-grade inflammation. Increasing evidence links gut microbiota dysbiosis to OA, but the mechanisms through which gut-derived perturbations contribute to joint...

Yu-Feng Zhou, Hong-Zhen Du, Qian Zhang et al. · 0 citations

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