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Yu-Han Zheng

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Open access Sep 2026

Reduced astrocytic Homer1a expression mediates mPFC excitatory synaptic dysfunction and neurodevelopmental deficits after maternal immune activation

Prenatal maternal immune activation (MIA) during pregnancy is a prominent environmental contributor to neurodevelopmental disorders and psychiatric conditions in offspring, but the precise brain-region- and cell-type-specific mechanisms remain unclear. Using a lipopolysaccharide (LPS)-induced MIA mouse model, we show...

Yu-Han Zheng, Xiao-Ru Sun, Xin Fang et al. · 0 citations

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