Open access
Oct 2026
Chitosan-Coated Calcium Alginate Microspheres Loaded with Alpha-Lipoic Acid/2-HP-β-CD Inclusion Complexes Enhance Aqueous Solubility and Enable pH-Responsive Intestinal Release
Alpha-lipoic acid (ALA) exhibits antioxidant and potential cardiovascular protective effects, but its insufficient stability in acidic environments and poor water solubility limit its oral delivery applications. In this study, the stability of lipoic acid in acidic environments was first evaluated through acid treatmen...
Yu Cui, Shi-Ya Huang, Ye-Ming Fu et al.
· International Journal of Mol... · 0 citations