TOP2A Overexpression as a Prognostic Biomarker in High-Grade Meningioma: An Integrated Single-Cell and Bulk Transcriptomic Study
While prior single-cell studies have identified proliferative neoplastic subpopulations, the prognostic and therapeutic implications of TOP2A focal copy-number status have not been defined. This study aimed to delineate the cellular architecture of high-grade meningioma and to evaluate the clinical and prognostic signi...