Author

Yu-Jiao Wang

2 papers indexed here

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Open access Oct 2026

A novel strategy to generate human iPSCs with enhanced mesodermal and endodermal differentiation capacity

Induced pluripotent stem cells (iPSCs) have unlimited proliferative capacity and multi-lineage differentiation potential. Autologous iPSC-derived cells reduce the risk of immune rejection, making them promising resources for regenerative medicine. However, iPSCs derived using conventional methods often show heterogenei...

Meng-Na Zhang, Ran Zheng, Yu-Jiao Wang et al. · Cell Regeneration · 0 citations

Open access Oct 2026

A dual-function XCL1-CD40L mRNA adjuvant potentiates cancer vaccines by coordinating DC recruitment and maturation

Background Despite the significant promise of mRNA tumor vaccines in treating solid tumors, their clinical response rate is constrained by the low effectiveness of antigen presentation resulting from the immune-suppressive tumor microenvironment (TME). Conventional type 1 dendritic cells (cDC1) are pivotal in antigen c...

Chun-Jie Wu, Wan-Xuan Shao, Ya-Di Liu et al. · Frontiers in Immunology · 0 citations