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Author

Yu Kang

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Aug 2026

Efficacy and safety of olezarsen in patients with vs without baseline fibrate use.

Olezarsen reduced triglycerides across the hypertriglyceridemia spectrum, with greater effects in patients on background fibrates, particularly with diabetes, to support potential complementary mechanisms and further investigation of concomitant triglyceride-reducing therapy.

Annabel Z. Wang, V. Alexander, T. Prohaska et al. · 1 citation
#machine learning Open access Jun 2026

Targeting the intrinsically disordered AR-NTD through a machine learning-based enhanced sampling workflow

An integrated computational workflow that combines enhanced sampling techniques and machine learning collective variables to identify druggable conformations of the AR-NTD and elucidate the binding mechanism of its modulator, EPI-002 is introduced.

Kai Zhu, Huating Wang, Jin-Tu Zhang et al. · 0 citations

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