Aug 2026
Berberine Attenuates Hypertrophic Phenotype in RAF1-Mutant Induced Pluripotent Stem Cell-Derived Cardiomyocytes through Suppression of ERK5-Cyclin D1 Signaling.
It is suggested that ERK5-Cyclin D1 signaling contributes to the hypertrophic phenotype of RAF1-mutant cardiomyocytes and support further investigation of BBR as a potential therapeutic candidate for RAF1-associated NS-HCM.
Hong-Fei Chen, Yu-Le Zhang, Xiao-Qi Lai et al.
· Cardiovascular Drugs and The... · 0 citations