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Review Open access Oct 2026

Multimodal biomarkers for early detection and immunotherapy assessment in hepatocellular carcinoma: integrating liquid biopsy, AI-based imaging and tumor immune profiling

A longitudinal framework integrating baseline blood, imaging and tissue features with on-treatment dynamics, preoperative reassessment and postoperative molecular surveillance is proposed, integrating baseline blood, imaging and tissue features with on-treatment dynamics, preoperative reassessment and postoperative mol...

Yu-Li Zhao, Xiao-Lei Chen, Han-Yuan Zhao · 0 citations
Open access Jul 2026

Metabolic-immunoregulatory subtypes reveal prognostic and therapeutic insights in multiple primary lung cancer

This study identified a metabolically distinct malignant epithelial subpopulation enriched in MPLC tumors, characterized by upregulation of amino acid metabolism pathways and active MHC-II-mediated interactions with immunosuppressive CD4+ Treg cells and mast cells.

Yu-Li Zhao, Han-Yuan Zhao, Hui-Sheng Wu et al. · 0 citations

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