Yu-Ling Su

Regulatory T cells in cardiac allograft vasculopathy: from mechanistic insights to clinical tolerance

Cardiac allograft vasculopathy (CAV) is the primary impairment that influences the long-term prognosis of transplanted hearts. CAV is characterized by diffuse intimal hyperplasia of the coronary arteries, which is mediated by chronic inflammation, the alloimmune response, and vascular remodeling. Current immunosuppress...