BACKGROUND
Brain metastases are a major clinical challenge with poor prognosis, particularly in patients with a history of smoking. While neurons are abundant in the brain and capable of synaptic interaction with tumor cells, their role in brain metastasis remains poorly understood. Emerging evidence suggests that neur...
Shih-Ying Wu, Abhishek Tyagi, Eleanor C. Smith et al.· Neuro-Oncology· 0 citations
Obesity is increasingly recognized as a chronic inflammatory condition, often driven by prolonged high-fat diet (HFD) consumption. Beyond causing metabolic dysregulation, obesity can disrupt immune-brain communication, contributing to the development of emotional disorders. During the early stages of HFD exposure, proi...
Findings support KATP channel functional state as a candidate link between metabolic stress, neuroimmune alterations, and dopaminergic circuit adaptations in female mice, and suggest KATP channel modulation as a potential therapeutic strategy for metabolic-associated depression.
Chung-Ling Chen, Pei-Yun Li, Hao-Yeh Tsai et al.· Brain, behavior, and immunit...· 0 citations
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