Optimization of esterase production from Monascus purpureus Y146 by artificial neural network-genetic algorithm and its application in flavor enhancement of fermented wine.
Esterases play an important role in flavor regulation during food fermentation. In this study, a high esterase-producing strain, Monascus purpureus Y146, was used to optimize esterase production via one-factor-at-a-time experiments (OFAT), response surface methodology (RSM), and an artificial neural network with geneti...