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Author

Yu-Ning Zhang

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2 papers indexed here

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Sep 2026

Mapping Cell-Type-Specific Regulatory Variants in Vascular Dementia by Integrating Single-Cell Chromatin Accessibility and Gene Expression.

BACKGROUND Vascular dementia (VaD), the second most common form of dementia, is a growing burden in aging populations and lacks disease-modifying therapy. Although immunerelated regulatory mechanisms are increasingly implicated, the role of immune cell-specific chromatin accessibility variants remains poorly understood...

Qiu-Han Xu, Zhao-Hui Chai, Yu-Ning Zhang et al. · 0 citations
Open access Jul 2026

Genetic regulation of cell type-specific chromatin accessibility contributes to migraine etiology.

Two non-neuronal brain open chromatin regions are prioritized as likely causal contributors to migraine risk and identified candidate regulatory elements and target genes for further mechanistic and translational investigation.

Qiuhan Xu, Zhao-Hui Chai, Yu-Ning Zhang et al. · 0 citations

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