Author

Yu-Peng Zhao

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Open access Sep 2026

Integrative multi-omics and experimental validation identify SERINC2 as a ferroptosis-related biomarker in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with limited therapeutic options. Ferroptosis, an iron-dependent cell death, has been implicated in various fibrotic diseases, but its role in IPF remains unclear. This study integrates spatial transcriptomics, single-cell RNA sequencing, and...

Si-Miao Chen, Xiang Zhou, Yu-Peng Zhao et al. · Clinical and Experimental Me... · 0 citations

Open access Aug 2026

scRNA‐Seq in Gastric Cancer Reveals Macrophage‐Derived C1q as a Diagnostic Marker

ABSTRACT Tumor‐associated macrophages (TAMs) and the complement system play pivotal roles in reshaping the chronic inflammatory microenvironment and driving malignant transformation. Although C1QA+ TAMs have been identified in multiple tumor types, their role in gastric cancer (GC) remains unexplored. Single‐cell RNA s...

Saisai Gong, Yu-Peng Zhao, Sheng Yang et al. · Cancer Science · 0 citations