Yu-Qian Chen

A triple-immunomodulatory quercetin nanoplatform to reinforce T-cell function and remodel tumor microenvironment.

Immune checkpoint inhibitors (ICIs) often exhibit limited clinical efficacy due to insufficient infiltration of T cells in the tumor microenvironment (TME). To address this challenge, we utilized quercetin, an active ingredient of traditional Chinese medicine, as an alternative ICI, and developed a hyaluronic acid-coat...