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Yu-Qin Liang

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Open access Aug 2026

Nfe2l2-knockout mouse model exhibits oxidative stress-associated stromal degeneration and inflammatory activation resembling keratoconus pathology

Data support a feed-forward axis in which NRF2 deficiency drives oxidative stress, inflammation, and extracellular-matrix degradation that extends to corneal innervation, while NRF2 supplementation partially mitigates these pathological changes.

Xiaoxue Li, Jia-Ning Gu, Xi-Hao Sun et al. · 0 citations

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