Yu-Ri Choi

Immune pathway activation in gastric cancers with LINE-1 retrotransposon overexpression and homologous recombination deficiency

There are only a few whole genome sequencing studies of human gastric cancer (GC) conducted so far. We performed comprehensive whole genome, bulk RNA, and methylation sequencing analyses of 100 samples of GC and adjacent normal tissue. In a smaller non-EBV/non-MSI subset (n = 23), we also performed proteomic profiling...