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Author

Yu-Shi Sun

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Oct 2026

SOCS1/Wnt/IL-1β axis negatively regulates macrophage extracellular traps and M1 polarization through the TNF pathway in crystalline kidney injury.

In the renal microenvironment of CaOx crystal deposition, IL-1β induces METs formation by activating the TNF signaling pathway and promotes M1 polarization, and SOCS1 and the TNF signaling pathway are identified as potential therapeutic targets for interrupting this positive feedback loop and mitigating sterile kidney...

Ze-Feng Xue, Yu-Shi Sun, Bo-Jun Li et al. · 0 citations

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