Open access
Sep 2026
Modulation of IKKβ deubiquitination dynamics by CYLD links microglia-neuron crosstalk to be involved in Alzheimer’s disease
Alzheimer’s disease (AD) is an age-related neurodegenerative disorder with limited therapeutic options. Microglia-mediated neuroinflammation plays a critical role in its pathogenesis. Depending on the microenvironment, activated microglia can adopt either a pro-inflammatory or an anti-inflammatory phenotype. Previous...
Qing-Hua Luo, Wei Wang, Xun-Hu Gu et al.
· Cell Death Discovery · 0 citations