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Author

Yu Wang

h-index 11 View on Semantic Scholar

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Sep 2026

Exosomal METTL16 from mesenchymal stem cells promotes malignant progression and M2 macrophage polarization in acute myeloid leukemia via IGF2BP2-dependent GPX1 m6A modification.

Exosomal METTL16 from AML-MSCs plays a crucial role in promoting leukemic cell survival and M2 polarization, and targeting this axis may provide a potential theoretical foundation to reverse M2 macrophage polarization and inhibit AML progression.

Zhen Shang, Mi Zhou, Si-Jia Yan et al. · 0 citations
Review Open access Jul 2026

Cellular Immunotherapy for Acute Myeloid Leukemia: From Bench to Bedside

It is concluded that while cellular immunotherapies represent a transformative frontier in AML treatment, their broad application is currently constrained by target antigen heterogeneity, a complex tumor microenvironment, and significant toxicities.

Yu Wang, Jia-Ying Wu, Xiao-Bing Huang et al. · 0 citations

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