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Yu-Xiang Yang

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Open access Jan 2026

SIAH1‐Mediated Ubiquitination and Degradation of TRIB3 Modulate Osteogenic and Adipogenic Differentiation

Background The imbalance between osteogenic and adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) is a key factor in osteoporosis (OP). TRIB3 acts as a molecular switch regulating this process. While E3 ubiquitin ligases are known to influence TRIB3 protein stability, the specific role of E3 liga...

Hao Lv, Hairu Yi, Ying-Hao Zhu et al. · 0 citations

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