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Yu-Xiao Xue

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Open access Sep 2026

Lactylation-mediated activation of HSPA5 upregulates VGLL3 expression to inhibit mitophagy-dependent ferroptosis following intracerebral hemorrhage.

Intracerebral hemorrhage (ICH) is a devastating neurological disorder characterized by extensive neuronal death, in which ferroptosis has emerged as a central pathological mechanism. Yet, the role of mitophagy in regulating ferroptosis during ICH remains elusive. Herein, we identified a lactylation-mediated HSPA5 (heat...

Qi-Xiang Zhang, Qi-Kai Tang, Bao-Feng Wang et al. · 0 citations

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