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Yuxin Hu

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Open access Jul 2026

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Consistently, 2DG or liproxstatin-1 reduced ferroptosis-associated oxidative damage and improved behavioral or cognitive deficits in transgenic C. elegans, supporting a substantial contribution of AMPK-ACC1-associated signaling to ferroptosis suppression under energy stress.

Yuanyuan Yong, Yu-Xin Hu, Qian Feng et al. · 0 citations

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