Adoptive cell therapy continues to encounter diverse hurdles in treating solid tumors, including poor infiltration, an immunosuppressive microenvironment, and tumor immune evasion, necessitating the endowment of effector cells with multiple functionalities. However, conventional cell-engineering techniques, including g...
Qing-Guo Zhong, Yu-Xin Huang, Zhen-Hua Li et al.· BME Horizon· 0 citations
The reconstruction of skull base defects after tumor resection remains challenging due to the limitations of conventional materials, including poor mechanical properties, uncontrolled degradation, and insufficient osteoinduction. In this study, we developed a novel poly(lactic acid)/gelatin (PLA/Gel) fibrous membrane i...
Yu-Xin Huang, Zhen-Dong Yang, Zhi-Tian Shi et al.· Journal of Biomaterials Scie...· 0 citations
This review surveys strategies spanning surface engineering to three-dimensional scaffolds to examine how nanoscale and hierarchical topographies on dense implants instruct protein adsorption and osteogenesis, then assess antibacterial coatings that must balance bactericidal potency with hostcell safety.
Chi Zhang, Jian-Xun Yao, Yu-Xin Huang et al.· NANO· 0 citations
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